阴茎血流指数(PFI)测定及其临床意义

The measurement of penile flow index and its significance

目的探讨阴茎血流指数(PFI)在勃起功能障碍(ED)筛查诊断中的临床意义。方法采用国产SW-3501男性功能诊断治疗系统中的血流多普勒探测仪测定37例主诉ED患者的左侧桡动脉和阴茎背动脉、双侧阴茎海绵体动脉的血流速度,求得PFI值;对6例PFI>6和随机抽取6例PFI<6的患者分别进行了彩色双功能多谱勒超声检查。结果阴茎疲软状态下37例患者的PFI值为0.9～8,平均(3.5±0.6)。其中有6例PFI>6,平均为(7.4±0.9),3 1例P FI<6,平均(3.3±0.5);随机抽取6例PFI<6的患者经彩色双功多普勒检查,其中1例诊断为血管性ED,余5例未发现异常;6例PFI>6的患者经彩色双功能多谱勒超声检查5例诊断为血管性ED,其中有1例PFI>8,考虑为动脉性ED。统计学上的诊断试验方法提示,其灵敏度和特异度均为83.3%,误诊率和漏诊率均为16.7%。结论 PFI的测定对血管性ED的诊断具有筛查意义,它是一种无创、简便、经济和实用的诊断方法 。

Objective To evaluate the value of penile flow index （PFI） in diagnosis of patients with ED. Methods Blood flow velocities of left brachial arteries and dorsal and cavernosal arteries of 37 cases with complaint of penile erectile dysfunction （ED） were measured for calculating PFI by SW-3501 male functional diagnosis and treatment system. Six patients with PFI more than 6 and 6 cases with PFI less than 6 randomly selected were examined by color duplex ultrasonography. Results PFI values of 37 ED patients with flaccid state were from 0.9 to 8 including 6 patients with PFI more than 6 （7.4±0.9） and 31 cases with PFI less than 6 （3.3±0.5）. The 5 cases of 6 patients with PFI more than 6 were diagnosed as mixed vasculogenic ED by color duplex ultrasonography. One of the 6 randomly selected cases with PFI less than 6was diagnosed as vasculogenic ED by color duplex ultrasonography. The diagnostic test showed the sensitivity and specificity were both 83.3%, the mistake diagnostic rate and omission diagnostic rate were both 16.7%. Conclusion PFI with no invasive, simplicity and feasibility was a valuable index for screening of vasculogenic ED.