无抽搐电休克治疗对精神分裂症患者认知功能的影响

Effect of Modified Electroconvulsive Therapy on Cognitive Functions in Schizophrenics

目的探讨无抽搐电休克治疗(MECT)对精神分裂症患者认知功能的影响。方法采用威斯康星卡片分类测验(WC-ST)和中国修订韦氏成人智力测验(WAIS-R)对46例精神分裂症患者在MECT治疗前后分别进行5次评定。结果 WCST持续反应数与持续错误数评分较治疗前有显著降低;治疗后3天,WCST总正确数、总错误数、完成分类数评分和操作智商、总智商较治疗前有显著提高,其中,WCST总错误数和完成分类数评分在治疗后2周与治疗后3天相比仍有显著提高;言语智商在治疗后2周与治疗后3天相比有显著提高。结论 MECT治疗对患者的操作技能可能有短暂且为可逆性的影响,而其他认知功能因子则随着MECT治疗会有不同程度的改善。

Objective To explore the effect of modified electroconvulsive therapy （MECT） on cognitive functions in schizophrenics.Methods A total of 46 cases of schizophrenia were recruited and measured with Wisconsin Card Sorting Test（WCST）and Revised Wechsler Adult Intellegence Scale （WAIS-R） before and after treatment with MECT.Results The scores of continuous reactions and continuous errors were significantly lower after treatment than before treatment. The scores of total correct,total errors,classified completion and operating intelligence quotient or total quotient were significantly higher in 3rd days after treatment than before treatment. Among those factors,the scores of total errors and classified completion were higher at the end of 2 weeks after treatment than in 3rd days after treatment,While speech intelligence quotients were significantly higher at the end of 2 weeks after treatment than in 3rd days after treatment.Conclusion MECT might have transient and reversible effects to operating skills of schizophrenics. And the patients＇ other congnitive functions might receive improvement in varying degrees with MECT.