盐酸屈他维林对小儿痉挛性腹痛的疗效观察

The Efficacy Observation of Drtaverine Hydrochloride in Treatment of Children Spastic Abdominal Pain

目的:观察盐酸屈他维林治疗小儿痉挛性腹痛的疗效。方法:将2008年5月至2010年5月我院儿科急诊痉挛性腹痛患儿100例随机分成盐酸屈他维林组和东莨菪碱组各50例,分别采用盐酸屈他维林和东莨菪碱治疗,并进行疗效比较。结果:盐酸屈他维林组的总有效率84%明显高于东莨菪碱组的74%,P<0.05;盐酸屈他维林组10～30 min后血Ca^(2+)浓度明显高于治疗前,P<0.05;而东莨菪碱组则无明显变化。结论:盐酸屈他维林对小儿痉挛性腹痛较东莨菪碱的疗效好。

Objective： To observe the efficacy of drotaverine hydrochloride in treatment of children spastic abdominal pain.Methods： 100 children suffered from spastic abdominal pain from May 2008 to May 2010 in our hospital pediatric emergency were randomly divided into drotaverine hydrochloride group and scopolamine group treated by drotaverine hydrochloride and scopolamine respectively, each group was 50 cases. The curative effect was compared between the two groups. Results： The total effective rate in drotaverine hydrochloride group and scopolamine group was 84% and 74% respectively. The total effective rate in drotaverine bydrochloride group was significantly higher than that in scopolamine group,P〈0.05. The blood Ca^2＋ level after treatment 10-30 min were significantly higher than before treatment in drotaverine hydrochloride group （P〈0.05） ,but no significant change in scopolamine group. Conclusion：The efficacy of drotaverine hydrochloride in treatment of children spastic abdominal pain is better than that of scopolamine.