从血清PA及Fn含量变化看急性腹泻对婴幼儿营养状态的影响

Effect of Acute Diarrhea in Children on Nutrition State

采用火箭免疫电泳技术测定了35例急性秋季腹泻患儿不同病程的微量血清前白蛋白（PA）及纤维结合蛋白（Fn）含量，以评估急性腹泻对患儿营养状态的影响。结果：急性腹泻患儿病程三天内的血清PA、Fn浓度均无明显变化，但从第三天开始则出现了随病程延长而逐渐下降的趋势，并在禁食组尤为显著。研究提示，作为评价营养状态敏感性生化指标的血清PA及Fn在急性腹泻患儿的动态变化说明，急性腹泻可导致明显的营养障碍，尤其是对腹泻期间采用不恰当禁食疗法者，其影响更为突出，应引起人们的高度重视。

In thes study, serum concertration of prealbumin (PA), fibrone-ctin (FN) were detrmined in 35 children with acute diarrhea by im-munodiffusion. The results showed that tha concentration of PA, FNwas nirmal within three days of course of disease. From the thirdd dayin course of disease, the concentration of PA and FN were decreasedgradually, and in children with eaten was prohibited were obvious.This study suggested that acute diarrhea in children could effect on nu-trition.