短程治疗胃食管反流症460例分析

Analysis of 460 Cases with GERD by Short-term Clinical Treatment

目的观察我院消化科门诊GERD病人内镜检出反流性食管炎情况及疗效。方法对460例有烧心等反流症状的病人行胃镜检查,根据镜下特点分为反流性食管炎(RE)组和非糜烂性反流病(NERD)组,两组病人同时给予2周莫沙比利及雷贝拉唑治疗,观察疗效。结果 460例患者中仅有124例有反流性食管炎,336例内镜检查无异常;两组病人在疗效上无差异(P>0.05)。结论反流症状与内镜表现不符,无论内镜下表现如何,莫沙比利与雷贝拉唑联合试验性短程应用,起到了治疗与诊断的双重效果,是诊断GERD最直接有效的途径。

Objective To investigate the endoscopic manifestations and the curative effect of GERD.Methods 460 cases with reflux symptom were devided into two groups of RE and NERD according to endoscopic manifestations,and observe the curative effect after two weeks＇treatment with Mosapride and Leibeirazole in both groups.Results Only 124 cases showed reflux esophagitis,while 336 cases were normol in endoscopic;There was no statistical difference in curative rates between the two groups （P0.05）.Conclusion The reflux symptom was not accorded with endoscopic manifestation,the application of Mosapride and Leibeirazole achieved a double effect of diagnosis and treatment,Which is a very direct and efficient means in the diagnosis.