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不同手术方式治疗Chiari畸形的疗效比较 被引量:3

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摘要 目的 探讨Chiari畸形不同手术方式的疗效差别.方法 Chiari畸形(部分合并脊髓空洞症)的患者62例,其中28例患者行单纯环枕筋膜切除和硬膜外层切开术(单纯硬膜外层切开组),34例患者行环枕筋膜切除,后颅窝扩大重建术(后颅窝扩大重建组).结果 两组患者无一例死亡,单纯硬膜外层切开组,27例术后临床症状有改善(96.43%),后颅窝扩大重建组,29例术后临床症状有改善(85.29%),两组有效率近期效果比较差异无统计学意义(P>0.05).术后门诊随访0.5~5(2.6±1.4)年.单纯硬膜外层切开组随访20例,临床改善19例;有效率为95%.后颅窝扩大重建组随访12例,临床改善7例;有效率为58.33%.两组有效率远期随访效果比较单纯硬膜外层切开组优于后颅窝扩大重建组(P<0.05).结论 单纯环枕筋膜切除和硬膜外层切开术是治疗Chiari畸形较为合理的术式,疗效优于后颅窝扩大重建术.
出处 《中国医师杂志》 CAS 2010年第7期917-919,共3页 Journal of Chinese Physician
基金 基金项目:辽宁省科技厅科技攻关课题(2008225010-9)
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参考文献12

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同被引文献39

  • 1刘彬,王振宇,李振东,马长城,陈晓东,孙建军.不同手术方式治疗ChiariⅠ畸形合并脊髓空洞的临床研究[J].中华神经医学杂志,2005,4(11):1137-1139. 被引量:25
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  • 6Zhang ZQ,Chen YQ,Chen YA,et al.Chiari I malformation associated with syringomyelia:a retrospective study of 316 surgically treated patients[J].Spinal Cord,2008,46(5):358-363.
  • 7Strayer A.ChiariⅠ malformation:clinical presentation management[J].J Neurosci Nurs,2001,33(2):90-104.
  • 8Tator CH,Megum K,Rowed DW.Favorable results with syringosubarachnoid shunt for treatment of syringomyelia[J].J Neurosurg,1982,56(4):517-523.
  • 9Levine DN.The pathogenesis of syringom yelia associated with lesions at the foramen magnum:a critical review of existing theories and proposal of a new hypothesis[J].J Neurol Sci,2004,220(1/2):3-21.
  • 10Zhang ZQ,Chen YQ,Chen YA,et al.Chiari Ⅰ malformation associated with syringomyelia:a retrospective study of 316 surgically treated patients[J].Spinal Cord,2008,46 (5):358-363.

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