摘要
目的:评价大孔吸附树脂富集山茱萸有效成分的应用效果。方法:UV法测定总苷的含量,RP-HPLC法测定莫诺苷及马钱苷的含量。结果:莫诺苷由药材含量的1.58%提高到51.00%,马钱苷由药材含量的0.62%提高到16.09%,总环烯醚萜苷由药材含量的4.54%提高到91.57%,结论:大孔吸附树脂富集工艺稳定,可显著提高成药的质量,从而生产出剂量小和质量稳定的可控制剂。
Objective： To evaluate the utilization effectiveness of the active ingredient of Fructus Macrocarpii enriched by macroporous resin.Methods： The content of the total glycosides was determined by meas of UV;the content of morroniside and loganin were determined using RP-HPLC.Results： Compared with material content,the morroniside content was increased from 1.58% to 51.00%,the loganin content was enhanced from 0.62% to 16.09%,the total iridoid glycoside content was improved from 4.54% to 91.57%,respectively.Conclusion： Macroporous resin enrichment process was stable and could significantly improve the quality of medicines,and thus could produce the small dose and stable quality control preparation
出处
《中医药学报》
CAS
2010年第4期43-45,共3页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金(编号:30572300)
黑龙江省科技攻关计划(编号:GA08C303)
关键词
莫诺苷
马钱苷
环烯醚萜总苷
Morroniside
Loganin
Total iridoid glycoside
