新生儿医院内感染监测和回顾性调查分析

Monitoring and retrospective study of neonate hospital infection

【目的】回顾性分析陕西省妇幼保健院3年新生儿科医院内感染监测资料,用以指导医院内感染的防控。【方法】对2006年1月—2008年12月资料进行回顾性调查和危险因素病例对照研究。【结果】3年来与住院时间相关的感染发生率轻度上升,以革兰氏阴性菌(G-)占76.7%,肺炎克雷伯杆菌占32.5%,革兰氏阳性菌(G+)占23.3%。药敏试验提示病原体对多种抗生素高度耐药。贫血、机械通气、长期住院是新生儿医院内感染的独立发病因素。【结论】医院感染的发生和多个因素有关,需要采取多重措施来预防。

【Objective】 To quide hospital infection control with retrospecfive study of reonate hospital infection（HI） data in the last three years. 【Method】 Monitoring and doing retrospective study of from January of 2006 to December of 2008. 【Results】 Infection rate associate with in-patient time was seemed slight elevation trend,Gram-negative（G-） bacteria took part in 76.7% pathogenic bacteria and Klebsiella pneumoniae contributed 32.5% highly of them.Gram-Positive（G＋） Bacteria were 23.3%.Drug sensitivity test cued pathogenic bacteria had high antibiotic resistance.The most important factors were mechanical ventilation,long term in-patient and anemia. 【Conclusion】 Infection rate associate with muti-factors and by muti-way to reduce HI rate.