倍频532激光治疗视盘新生血管型糖尿病视网膜病变观察

Therapeutic effect of 532nm frequency-doubled laser photocoagulation on proliferative diabetic retinopathy with disc neovascularization

目的探讨倍频532激光治疗视盘新生血管型糖尿病视网膜病变(DR)的疗效。方法对67例(109只眼)视盘新生血管型DR患者行超全视网膜光凝。激光治疗后1、3、6、12个月行荧光素眼底血管造影(FFA)检查,新生血管未消退者追加光凝。随访24～36个月(平均32.8个月)。结果光凝术后视力提高者19只眼(17.43%),视力不变者63只眼(57.80%),视力下降者27只眼(24.77%)。经一次或多次追加光凝,最终71只眼(65.14%)新生血管消退,14只眼(12.84%)新生血管变细变少,24只眼(22.02%)新生血管无变化或加重。激光治疗量为2650(1600～5450)点。结论倍频532激光治疗视盘新生血管型DR安全有效。

Objective To investigate the effect of 532 nm frequency-doubled laser photocoagulation on proliferative diabetic retinopathy（PDR） with disc neovascularization（NVD）.Methods 109 eyes of 67 patients with NVD were treated with extra panretinal photocoagulation by 532nm frequency-doubled laser.The fundus fluorescein angiography was performed at1、3、6、12 months after the treatment.The further photocoagulation was complemented for the patients who remained newvessels.The follow-up period was 24 ～ 36 months（mean 32.8 months）.Results After extra panretinal photocoagulation,vision was improved in 19 eyes（17.43%）,unchanged in 63 eyes（57.80%） and decreased in 27 eyes（24.77%）.After one or more additional photocoagulation,neovascularization entirely regressed in 71 eyes（65.14%）,partly regressed in 14 eyes（12.84%） and unchanged or aggravated in 24 eyes（22.02%）.The number of laser was 2650（1600 ～ 5450） points.Conclusion The treatment of 532nm frequency-doubled laser photocoagulation on proliferative diabetic retinopathy（PDR） with disc neovascularization is a safe and effective.