肺癌患者伴发弓形虫感染分析

Survey of Toxoplasma gondii Infection in lung cancer patients.

目的了解肺癌患者伴发Tox感染情况,为进一步治疗提供依据。方法采用酶联免疫法(ELISA)检测63例肺癌患者和293例其它呼吸系统疾病患者血清Tox-IgM、IgG抗体。结果 63例肺癌患者Tox-IgM阳性率为20.63%(13/63)、Tox-IgG阳性率为17.46%(11/63),293例其它呼吸系统疾病患者Tox-IgM阳性率为3.41%(10/293)、Tox-IgG阳性率为7.85%(23/293),二者差异有统计学意义(P<0.01,P<0.05);其中男性Tox-IgM阳性率为20.00%(8/40)、Tox-IgG阳性率为17.50%(7/40),女性Tox-IgM阳性率为21.74%(5/23)、Tox-IgG阳性率为17.39%(4/23),不同性别之间差异无统计学意义(P>0.05)。结论肺癌患者与呼吸系统其它疾病包括肺结核、胸膜炎、肺炎等患者相比,其Tox-IgM、IgG抗体阳性率明显高于其它,以IgM尤为明显。

Ahn To survey Toxoplasma gondii infection in lung cancer patients. Methods Specific IgG and IgM to Toxoplasma gnndii were detected by using ELISA among 63 lung cancer patients and 293 other respiratory patients. Results Among 63 lung cancer patients, the Tox-IgM positive rate was 20.63%（ 13/63 ）, and the Tox-IgG positive rate was 17.46% （11/63）. Among 293 other respiratory patients,the Tox-IgM positive rate was 3.41% （10/293）, and the Tox-IgG positive rate was 7.85% （23/293）.showing significant difference between these two groups （P〈0.01 ,P〈0.05）. The male Tox- IgM positive rate was 20.00%（8/40）,Tox-IgG positive rate was 17.50%（7/40）,and the female Tox-IgM positive rate was 21.74% （5/23）,Tox-IgG positive rate was 17.39%（4/23）,without significant difference between two genders （P〉0.05）. Conclusion The infection rate of Toxoplasma gondii in lung cancer patients＇ is obviously higher.