某院治疗儿童社区获得性肺炎的抗菌药物应用情况分析

The Analysis of The Application of Antibacterial Drugs in Treating Children with Community-acquired Pneumonia on A Hospital

目的调查某院儿童社区获得性肺炎治疗中抗菌药物的用药情况,促进临床合理用药。方法根据《抗菌药物临床应用指导原则》及《儿童社区获得性肺炎管理指南(试行草案)》等相关材料,对2006年1月至2009年6月在某院经病理检查,确诊为社区获得性肺炎的280例患儿的病案资料进行回顾性分析。结果抗菌药物的使用总例数达558例次,涉及十大类29品种;其中使用率前5位抗菌药物为头孢曲松钠(22.9%)、阿奇霉素(19.5%)、喜炎平(14.3%)、头孢呋辛钠(12.5%)和头孢他啶(9.9%);抗菌药物联合用药方式以头孢菌素类+阿奇霉素或喜炎平为主。结论某院儿童社区获得性肺炎治疗中抗菌药物的选择及用法用量基本合理,但细菌培养送检率及敏感试验率有待提高。

Objective To investigate the application of antibiotics drug in treating children with community-acquired pneumonia on a hospital in order to promote the clinical use of drugs. Methods To retrospectively analyzed the medical record data of children with community-acquired pneumonia diagnosed by the pathological examination from January 2006 to June 2009 by in a hospital according to the Guiding Principles of clinical use of antibiotics and Children of community-acquired pneumonia management guidelines （Trial Draft） and other related materials. Results The total number of antimicrobial drug cases reached 558 cases, involving ten classes of 29 species; in which the top fi ve antimicrobial drugs usage were Ceftriaxone （22.9%）, azithromycin （19.5%）, Xiyanping （14.3%）, Cefuroxime sodium （12.5%） and ceftazidime （9.9%）; the dominated antibacterial drug combination therapy approach to the cephalosporins or azithromycin＋Xiyanping. Conclusion The antimicrobial drug dosage and selection in treating children with community-acquired pneumonia in a hospital were basic reasonable, but the rate of bacterial culture and sensitivity test rates needed to be further improved.