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血清脂联素水平变化与脑梗死的关系

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摘要 目的观察脑梗死患者血清脂联素水平的变化及其临床意义,同时探讨其与一些脑梗死危险因子(肥胖、糖尿病)的相关性。方法选取120例脑梗死患者入选研究,以及40例健康成人作为对照组,检测脑梗死患者血清脂联素水平,并探讨其与脑梗死体积、BMI指数及糖尿病等的相关性。结果脑梗死组与正常对照组相比脂联素显著降低。2型糖尿病脑梗死患者与非糖尿病脑梗死患者相比脂联素显著降低。大梗死灶患者血浆脂联素水平明显低于中小梗死灶患者。肥胖者脂联素水平明显低于非肥胖者。脂联素水平与脑梗死体积、BMI指数及糖尿病呈负相关。结论脂联素水平降低是脑梗死发生和复发的独立危险因素,也是脑梗死的结果 ;脂联素水平与梗死面积呈负相关,因而脂联素可以作为神经损伤的标识物。
作者 何洪波
出处 《中国医药指南》 2010年第24期54-55,共2页 Guide of China Medicine
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