布洛芬治疗宫内节育器致经量增多的临床观察

A clinical observation of therapeutic effect of ibuprofen on menorrhagia due to IUD placement

目的 观察应用布洛芬治疗放置宫内节育器引起的月经量增多、经期延长及腰骶部疼痛的临床疗效.方法 选取因放置宫内节育器后出现月经量增多、经期延长伴腰骶部疼痛等症状的患者80例,随机分为布洛芬组（50例）和对照组（30例）,布洛芬组于月经来潮第1天开始口服布洛芬每次200mg,每天3次;对照组给予安络血每次5mg,每天3次,连续5天为1个疗程.共用药3个疗程.观察经量、经期及临床症状的变化并详细记录.结果 布洛芬组总有效率为100%,对照组总有效率53.3%,布洛芬组治疗效果明显优于对照组,有显著性差异（χ^230.7,P〈0.01）.结论 布洛芬应用于宫内节育器引起的月经量增多、经期延长、腰骶部疼痛效果明显,治愈率高,不良反应较轻,复发率低,值得临床推广.

Objective To observe therapeutic effect of ibuprofen on menorrhagia, menostaxis and pain in lumbosacral region after intrauterine device （IUD） placement. Methods 80 patients suffering from menorrhagia, menostaxis and pain in the lumbosacral region after IUD placement were divided into ibuprofen group （n =50） and control group （n =30） randomly. The patients in the ibuprofen group were given 200mg of ibuprofen three times per day for 5days since the 1st day of menstruation and those patients in the control group were given 5rag of carbazochrome three times per day for 5 days. All patients received 3 courses of treatment respectively. Results The total effective rates in the ibuprofen group and the control group were 100% and 53.3% respectively, showing that the clinical therapeutic effect of ibuprofen was much better than that of carbazochrome （x^2 = 30. 7,P 〈 0.01 ）. Conclusion Ibuprofen is effective for menorrhagia, menostaxis and pain in the lumbosacral region caused by IUD placement.