呼吸机相关肺炎36例临床分析

Clinical analysis of 36 rentilator-associated pneumonia

目的探讨呼吸机相关肺炎（VAP）的致病因素、病原菌分布、治疗及预防措施。方法回顾性分析36例VAP患者临床资料、致病菌及治疗方案等。结果 VAP发生率为5.5%,病死率为22.2%。主要致病菌为革兰阴性杆菌（66.0%）,以铜绿假单胞菌、肺炎克雷伯菌和大肠埃希菌为主;革兰阳性球菌占25.5%,主要为金黄色葡萄球菌;真菌占8.5%,主要为白色念珠菌。结论对机械通气患者采取积极有效预防,及时有效应用抗菌药治疗和综合治疗,可以减少VAP发生率,降低病死率。

Objective To investigate the etiological factors,pathogenic bacterium,measure of treatment and prevention.Methods The clinic data,pathogenic bacterium and therapeutic regimen of 36 patients suffered from ventilator-associated pneumonia（VAP） were analyzed retrospectively.Results The incidence rate of VAP and mortality rate in this group was 5.5% and 22.2% respectively.The main pathogenic bacterium were Gram-Negative bacillus,which taken up of 66.0%,and commonlly included Pseudomonas aeruginosa,klebsiella pneumoniae and escherichaiacoli.Gram-positive coccus and eumycete were hold 25.5% and 5.5%respectively.The former were chiefly Staphylococcus aureus and the later were Blastomyces albicans.Conclusion Active prevention,effective antibiotics and combined therapy can decrease the incidence rate of VAP and cut down mortality rate.