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重庆市璧山县2年出生缺陷调查结果分析 被引量:1

Analyzing monitor results of birth defect of Bishan County of Chongqing in 2 years
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摘要 目的调查壁山县妇幼保健院新生儿出生缺陷发生情况,了解出生缺陷相关因素,为进一步实施干预、有效的诊断和治疗提供依据。方法采用回顾性调查方法,对2004年4月至2006年4月出生缺陷资料进行流行病学描述性分析和统计学分析。结果出生缺陷发生率为13.39‰,最常见出生缺陷依次为面颈部缺陷、运动系统缺陷、中枢神经系统缺陷;25~29岁年龄组出生缺陷发生率最低;男性畸形明显多于女性畸形;部分出生缺陷有较明确的有毒、有害物质感染或接触史;出生后通过临床症状和体征确诊或产前通过B超检查确诊。结论做好出生缺陷预防工作,提高产前诊断水平,通过孕前、孕期干预措施,才能有效降低出生缺陷发生率。 Objective To investigate birth defect of MCH Hospital of Bi San county and correlation factor of birth defect.Supplying base for effective diagnosis and therapy.Methods Use retrospective ascertainment methods.Data of birth defect between April 2004 and April 2006 was epidemic described and statistically analyzed.Results Incidence of birth defect was 13.39‰.Most frequent birth defects were face-neck defect,locomotor system defect,central nervous system deficit.Incidence of birth defect in 2529 years old was lowest.Incidence of male deformity was more than that of female deformity.Some birth defects were infected and contacted with poisonous,noxious substance.Final diagnosis method was postnatal clinical diagnosis or antepartum ultrasound B diagnosis.Conclusion Preventing birth defect and elevating antenatal diagnosis level to depress the incidence of birth defect.
出处 《重庆医学》 CAS CSCD 北大核心 2010年第16期2194-2195,2197,共3页 Chongqing medicine
关键词 出生缺陷 监测 产前诊断 birth defect monitor antenatal diagnosis
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  • 1张水平,梁艳,刘淑芳,郝建武,刘璐,刘黎明,曹朝侠,相晓妹.围产儿42272名出生缺陷分析[J].中国儿童保健杂志,2004,12(3):259-261. 被引量:12
  • 2周树森,保毓书,赵树芬,郑青,许清,路锦绣,赵春燕,王兵,刘志敏,王志萍.苯系混合物对女工妊娠经过及妊娠结局影响的研究[J].中华劳动卫生职业病杂志,1993,11(5):265-268. 被引量:20
  • 3Latini G, DeFelice C, Presta G, et al. In utero exposure to di - (2 - ethylhexyl) phthalate and duration of human pregnancy [ J ]. EnvironHealth Perspect, 2003, 111 (14): 1783 - 1785.
  • 4Herbst A, Scully R. Adenocarcinoma of the vagina in adolescence. A report of 7 cases including 6 clear - cell carcinomas [ J ]. Cancer,1970, 25:745 - 757.
  • 5Hwang S, Beaty T, Panny N, et al. Association study of transforming growth factor alpha(TGF alpha)Tapl polymorphism and oral clefts: Indication of a gene - environment interaction in a population - based sample of infants with birth defects[J]. Am J Epidemiol, 1995, 141 (7) :629 - 636.
  • 6Richard M Sharpe, D Stewart Irvine. How strong is the evidence of a link between environmental chemicals and adverse effects on human reproductive health? [J]. BMJ, 2004, 328(21 ): 447 - 451.
  • 7Ferencz C, Loffredo CA, Correa Villasasnor A, et al. Risk factros for pulmonary valve stenosis[J ]. Teratology, 1996, 52(2) : 110.
  • 8Vinceti M, Rovesti S, Bergomi M, et al. Risk of birth defects in a population exposed to environmental lead pollution[J ]. Sci Total Environ, 2001, 278(3) :23 - 30.
  • 9Engel RR, Smith AH. Arsenic in drinking water and mortality from vascular disease: an ecologic analysis in 30 countries in the United States[J]. Arch Environ Health, 1994, 49(5) :418 - 427.
  • 10Loffredo CA, Beaty TH, Silbergeld EK. Solvent and paint exposure interact with polymorphisms in glutathione - S - transferase genes to increase the risk of congenital heart defects[J]. Teratology, 1997, 55 (1):42.

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  • 1周幸,刘鸿,王应雄,李力,李红,计垣,吴秦.出生缺陷调查资料的分析与思考[J].重庆医学,2006,35(24):2233-2235. 被引量:2
  • 2王经论,高锦声.病残儿疾病学[M].北京:中国人口出版社,1998.218-220.
  • 3Botto LD, Yang Q. 5, 10-Methylenetetrahydrofolate re- ductase gene variants and congenital anomalies: a HuGE review[J]. Am J Epidemiol, 2000,151 (9) :862-877.
  • 4Bianchi F, Calzolari E, Ciulli L, et al. Environment and genetics in the etiology of cleft lip and cleft palate with reference to the role of folic acid[J]. Epidermiol Prev, 2000,24(1):21-27.
  • 5Eric M,Vuckovic N,Pilija V,et al. Occurrence of congen- ital malformations in dead fetuses and neonates autopsied between 1991 and 2001 at the Institute of Pathology and Histology in Novi Sad[J]. Med Pregl, 2003,56 (7/8) : 373- 376.
  • 6Canfield MA, Collins JS, Botto LD, et al. Changes in the birth prevalence of selected birth defects after grain forti- fication witll fotic acid in the Unite States:Findings from a multi-state population based study[J]. Birth Defects Res A Clin Mol Terato,2009,73(10):679-689.
  • 7孙冬韦,刘丽,郝滨.孕妇与儿童铅中毒研究进展[J].中国妇幼保健,2001,16(6):385-387. 被引量:25

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