摘要
目的探讨利多卡因-氯胺酮合剂(以下简称利氯合剂)静脉麻醉在小儿眼科斜视手术中的应用效果。方法择期手术患儿60例随机分为3组:氯胺酮肌注+静脉麻醉组(A组)、氯胺酮静脉麻醉组(B组)和利氯合剂静脉麻醉组(C组)。记录并比较各组在麻醉前、诱导后、手术开始及术毕时循环功能和呼吸功能变化以及氯胺酮用量、术后苏醒时间和并发症。结果各组的苏醒时间分别为(24.2±5.8)min、(16.8±4.2)min及(10.3±4.6)min,和A组比较,B、C组的苏醒时间明显缩短(P<0.05);和B组比较,C组的苏醒时间明显缩短(P<0.05)。离开恢复室时间分别(39.7±4.3)min、(24.1±3.6)min及(15.6±3.2)min,和A组比较,B、C组的离开恢复室时间明显减少(P<0.05);和B组比较,C组的离开恢复室时间明显减少(P<0.05)。氯胺酮用量各组分别为(8.44±0.62)mg/kg、(5.48±0.84)mg/kg及(3.52±0.46)mg/kg,C组显著少于A组和B组(P<0.05)。结论在小儿斜视手术麻醉中,利氯合剂静脉麻醉效果优于单用氯胺酮麻醉。
Objective To observe the effects of lidocaine combined with ketamine in the pediatric strabismus surgeries.Methods 60 children were scheduled for strabismus surgery.They were divided into three groups randomly.A group:the patients were given ketamine by muscle and vein;B group:the patients were given ketamine by vein;C group:the patients were given lidocaine combined with ketamine by vein.The circulatory and respiratory functions were monitored.The parameters at four points were compared:before anesthesia,after induction,at the beginming and the end of operation.The dosage of ketamine,recovery time and complications were also recorded.Results The recovery time of groupA,B,C was(24.2±5.8)min,(16.8±4.2)min and(10.3±4.6)min respectively,compared with the group A,it was shorter than that of group B and C(P0.05);compared with the group B,it was shorter than that of group C(P0.05).The time stayed in PACU of group A,B,C was(39.7± 4.3)min,(24.1±3.6)min and(15.6±3.2)min respectively,compared with the group A,it was less than that of group B and C(P 0.05);compared with the group B,it was less than that of group C(P0.05).The dosage of ketamine in group A,B,C was(8.44± 0.62)mg/kg,(5.48±0.84)mg/kg and(3.52±0.46)mg/kg respectively,compared with the group C,it was less than that of group A and B(P0.05).Conclusion Compared with the usage of ketamine alone,lidocaine combined with ketamine is more effective in pediatric strabismus surgery.
出处
《中国现代医药杂志》
2010年第8期57-59,共3页
Modern Medicine Journal of China
关键词
利多卡因
氯胺酮
斜视
麻醉
Lidocaine Ketamine Strabismus Anesthesia