老年人与青中年急性脑梗塞静脉溶栓治疗的比较

A comparison between the elder and the younger on the thrombolytic therapy of acute cerebral infarction

评价老年人急性脑梗塞尿激酶静脉溶栓治疗的有效性和安全性。方法分析２６例急性脑梗塞病人静脉溶栓治疗的临床资料，以６０岁为界分为老年组和青中年组进行比较。结果①老年组和青中年组均有良好的疗效，有效率依次分别为６２．５％和７０．０％；②出血合并症在老年组较多，但多数为轻微皮肤出血；③溶栓后再梗塞的机会老年组较多。结论用尿激酶静脉溶栓治疗老年人急性脑梗塞与青中年患者相比同样有效，也比较安全，但溶栓后再梗塞的机会较多。

Objective To evaluate efficacy and safety of thrombolytic therapy withintravenous urokinase (UK) in acute cerebral infarction (ACI) of the elder patients. MethodTwenty-six patients with ACI were studied clinically with CT scan or MRI/MRA before and afterthrombolytic therapy with intravenous UK. Of them, sixteen were over sixty years old (60~77)the elder group ; ten were below sixty years old (38~58) the younger group. Result (l) Theclinical outcome of thrombolytic therapy with intravenous UK were good in both groups, the rateof efficacy was 62. 5% in the elder group and 70% in the younger. (2)The edler group seemed tohave more hemorrhagic complications, but most of them were mild skin hemorrhage. (3) Thechance of reinfaction after treatment was more often in the elder groups. Conclusion The efficacyof thrombolytic therapy with intravenousUK in the elder patients is as good as in the younger, andit seems to be safe too, except for the chance of re-infarction is more in the elder group.