HPLC测定山七降脂通脉胶囊中丹参酮Ⅱ_A和丹酚酸B的含量

Determination of TanshinoneⅡ_A and Salvianolic Acid B in Sanqi Jiangzhitongmai Capsule by HPLC

目的:建立山七降脂通脉胶囊的质量标准。方法:采用HPLC法测定制剂中丹参酮ⅡA及丹酚酸B的含量。结果:丹参酮ⅡA在0.051～0.255mg·L-1浓度范围内呈良好的线性关系(r=0.9992);丹酚酸B在0.41～2.07mg·L-1浓度范围内呈良好的线性关系(r=0.9997);结论:建立的分析方法简便可行,专属性强,可用于山七降脂通脉胶囊的质量控制。

Objective：To study the qualitative and quantitative methods for Sanqi Jiangzhitongmai Capsule. Method：The content of tanshinoneⅡA and salvianolic acid B was determined by HPLC. Result：The linear range of tanshinoneⅡA and salvianolic acid B was 0. 051 ～ 0. 255 mg·L -1 and 0. 41 ～ 2. 07 mg·L -1,respectively. Conclusion：The method set up by this study was accurate and easy to perform,and could effectively control the quality of Sanqi Jiangzhitongmai Capsule.