乙醇中毒小鼠肝、胃病理形态学特征及解酒口服液的保护作用

Pathomorphology of Ethanolised Mice Liver & Stomach and Protective Effects of the Soberup Oral Fluid

给小鼠连续灌胃二锅头白酒１０ｄ，造成小鼠连续醉酒，观察其肝、胃病理形态变化的特征，并探讨解酒口服液的作用。结果显示，乙醇中毒小鼠的肝脏组织病理改变符合人类嗜酒者肝脏病理形态学的特征，解酒口服液对其肝细胞弥漫脂肪变性、炎性细胞浸润及中央静脉周围纤维增生状态均具有显著的良性影响。

Continuously perfuse the mice stomach with white spirit Er Guotou for 100 days. Observe the pathomorphology of the liver and stomach and discuss effects of the Soberup' Oral Fluid (SOF). Results show that, liver pathologic change of the ethanolised mice was in accordance with the pathomorphology of the human body. SOF has a remarkably benign effect on the hepatocyte diffuse fatty degeneration, inflamatory celluar infiltration and the pericentral venous fibroplastic proliferation. It also has a protective effect on the pathological damaged gastric mucosa.