摘要
目的:探讨中药注射剂致敏反应实验研究概况,为中药注射剂的研究及应用提供思路。方法:概括归纳近年来国内外中药注射剂致敏性相关实验研究。结果:中药注射剂的过敏性抗原物质尚不明确,研究尚缺乏系统性,对致敏因素、致敏模型的研究还处于摸索阶段。结论:加强绿原酸及附加剂的抗原性研究,建立致敏动物模型,充分利用免疫化学和免疫芯片技术,为中药注射剂的开发和应用,提供新的研究思路。
Objective:To review the progress of sensitization reaction experiment research with Traditional Chinese medicine injections (TCMI). Method:The experimental studies on sensitization reactions of TCMI were summed up. Result:The result shows that the studies lack systematicness. The researches on allergic sensitization factors and sensitization model are still in the stage of exploration. Conclusion:To provide new ideas,the research on chlorogenic acid and additives antigen should be strengthened,the animal models of allergen and the techniques of immune-chemistry and immune-chip should be fully utilized for the development and application of TCMI.
出处
《中国实验方剂学杂志》
CAS
北大核心
2010年第10期204-206,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
中医药行业科研专项(200707008)
关键词
绿原酸
中药注射剂
致敏反应
chlorogenic acid
traditional Chinese medicine injections
sensitization reaction