口服结肠靶向制剂中辅料的应用

Application of Excipients for Oral Colon-targeting Drugs

目的:介绍辅料在口服结肠靶向制剂中的应用,为更深入的研究提供参考。方法:通过查阅国内外大量相关文献,对常用于口服结肠靶向制剂的几种辅料及其相应的释药系统进行分析概述。结果:辅料是药物制剂的基础材料和重要组成部分,在口服结肠靶向制剂的发展和生产中起关键作用。结论:辅料的选择对制剂的结肠定位起至关重要的作用。

Objective：To introduce the application of excipients for oral colon-targeting drugs,and to provide the reference for future research. Method：Through studying a great number of relevant literatures home and abroad,the authors analyses and outlines several kinds of commonly used excipients and their corresponding delivery systems. Result：Excipient is an important component and the basic material of pharmaceutical preparations. It plays a key role in the development and production of oral colon-targeting drugs. Conclusion：The choice of excipients plays a vital role for colon-targeting.