4Dikkes P Jaffe D B,Guo WH,et al.IGF2 knock out mice are resistant to kainic acid-induced seizures and neurodegeneration[J].Brain Research,2007;1175:85.
5Johnston BM.Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischenfic injury in fetal lambs[J].J Clin Invest,1996;97(2):300.
6Brabara M Johnston K,Carin M,et al.lnsulin-like growth factorl is a potent neuronal rescue got after hypoxic-ischemic injury infetal lambs[J]J Clin Invest,1996;97:300.
7Lee WH,Wang GM,Seaman LB,et al.Coordinate IGF-1 and IGFBP gene expression in perinatal rat brain after hypoxia-ischemia[J].J Cereb Blood Fbw Metab,1996;16:227.
8Hodge RD,D'Ercole AJ,O'kusky JR,et al.lnsulin-like growth factor-1 accelerates the cell cycle by decreasing G1 phase length and increases cell cycle reentry G1 phase length and increases cell cycle reentry in the embregoninc cerebral corexl[J].Neurosci,2004,24(45): 10201.
9Mackay KB,Loddick SA.Neuroprotective elects of insulin- like growth factor-binding protein ligand inhibit-tors in vitro and vivo [I].J Cereb Blood flow Metab,2003;23(10): 1160.
10Wojnar MM,Fan J,Frost AM,et al.Ahemation of the insulin-like growth factor system in trauma patiens [J].Am J Physiol,2000;268 : 970.
