摘要
目的探讨原发性高血压(EH)、肾实质性高血压(RH)和肾血管性高血压(RVH)患者红细胞镁含量(EMC)、Mg2+/Na+交换速率(VNDmax)及其与血压的关系。方法原子吸收光谱火焰法。结果(1)EH组的EMC[(2.03±0.06)mmol/L]显著较正常对照组(2.16±0.04)、RH(2.17±0.05)和RVH(2.15±0.04)组低,而VNDmax[(155.3±15.2)μmol·L-1·h-1]显著较另外三组高(分别为96.8±13.2、94.3±14.2和97.3±12.5)。(2)EH组VNDmax与舒张压显著相关(r=04872,P<005)。结论(1)EH患者VNDmax明显升高,是造成EMC低下的原因,可能在疾病的发生发展中起一定作用。(2)RH、RVH患者细胞镁代谢状况无异常。
Objective To investigate the erythrocyte magnesium content (EMC), magnesiumsodium
exchange rate (VNDmax) and its relationship with blood pressure in patients with essential
hypertension (EH), renal parenchymal hypertension(RH) and renal vascular hypertension(RVH).
Methods EMC and VNDmax were measured by flame assay of atomic absorption
spectrophotometry. Results (1) EMC in EH group 0.06)mmol/L] was significantly lower than
normal control(2.160.04), RH(2.170.05) and RVH(2.150.04) group, while VNDmaxh-1]was
significantly higher than other three groups (96.813.2, 94.314.2 and 97.312.5respectively). (2)
VNDmax in EH group closely correlated to diastolic blood pressure (r=0.4872, P<005).
Conclusion (1)VNDmax increases in EH,which is the cause of low EMC and might contribute to
the pathogenesis of the disease. (2) cellular magnesium metabolism is not abnormal in RH and
RVH.
出处
《中华肾脏病杂志》
CAS
CSCD
北大核心
1999年第2期107-110,共4页
Chinese Journal of Nephrology
关键词
高血压
镁/代谢
离子交换
HypertensionMagnesium/sodiummetabolismIon exchange