餐后血糖临界孕妇临床干预的探讨

Clinic intervention of postprandial 2 hour plasma glucose borderline pregant women

目的对餐后血糖临界孕妇进行临床干预并探讨其母婴结局。方法在我院产科门诊产检的孕妇,于孕24-28周直接进行糖耐量试验(OGTT),排除GDM及IGT的病例,其余的孕妇中OGTT2h的血糖值在6.7-7.8mmol/L之间的孕妇,随机分为研究组与对照组,研究组(150例),进行糖尿病规范管理,进行相关宣教及饮食运动治疗;对照组(146例),不做特殊处理。每次产检复查餐后2h血糖,共复查3次,观察血糖变化。比较两组孕妇的母儿预后。结果研究组OGTT2h的血糖平均值7.20±0.32mmol/L,对照组7.16±0.36mmol/L,两组无显著性差异,三次复查餐后2h血糖,两组均无显著性差异。两组孕妇的顺产率、产钳率、剖宫产率比较,差异无统计学意义。两组新生儿平均出生体重无显著性差异。两组新生儿平均血糖、巨大儿比率及新生儿并发症的发生率均无显著性差异。结论餐后血糖临界孕妇经过临床干预后母婴结局无明显改变。

Objective：To investigate the Clinic intervention of postprandial 2 hour plasma borderline pregnant women and maternal and fetal outcome.Methods：The pregnant women delivered in Aviation Industry Central Hospital,were received glucose tolerance test between 24-28 gestational weeks.Excluding cases of GDM and the IGT,The OGTT 2h plasma glucose level of the rest of the pregnant women were 6.7-7.8mmol /L,The women were randomly divided into research group and control group.The research group（150 cases） were received diabetes mellitus management and diet and exercise therapy,the control group（146 cases）,will not do special processing.The postprandial 2 hour plasma glucose was reviewed each check,a total of three times to observe the changes in plasma glucose.Compared two groups of pregnant women,children prognosis of the mother.Compare the final result of the pregnant women and perinatal infants.Results：The OGTT 2h average plasma glucose of research group is 7.20 ± 0.32 mmol/L,The control group is 7.16 ± 0.36 mmol/L,no significant difference between the two groups,The postprandial 2 hour plasma glucose was reviewed,there was no significant difference between the two groups.There were no significant difference in the rate of spontaneous labor,forceps delivery and cesarean section.The average birth weight was no significant difference between the two groups.Two groups of newborn average blood glucose,macrosomia ratio and the incidence of neonatal complications was no significant difference.Conclusions：postprandial 2 hour plasma glucose borderline pregant women after clinical intervention,no significant change in the maternal and fetal outcomes.