2006-2008年我院用抗菌药物的回顾分析

Retrospective analysis of antibacterial drug used in our hospital during 2006-2008

目的:分析掌握我院抗菌药物的使用情况,为临床合理应用抗菌药物提供依据。方法:利用医院HIS系统,收集我院2006年1月-2008年12月抗菌药物的出库销售数据。采用频度分析和金额排序的方法作统计分析。结果:抗菌药物用药占用药总金额的28.18%～29.62%;消耗金额最大的是头孢菌素类,其次为喹诺酮类和青霉素类;用药频度较大的是头孢菌素类、青霉素类、喹诺酮类和大环内酯类;消耗金额排序靠前的药物是左氧氟沙星注射液、头孢曲松钠、头孢西丁钠、头孢呋辛钠等;用药频度排序每年有所变化,靠前的药物是阿莫西林胶囊、罗红霉素胶囊、头孢曲松钠、左氧氟沙星注射液等。结论:我院抗菌药物的使用结构基本合理。抗菌药物比例、"特殊使用"的抗菌药物、头孢菌素类药物的应用缺乏合理性,还需进一步加强管理,促进合理用药。

Objective： To analyze antibacterial drug used in our hospital for the rational use of antibiotics in clinic. Methods： Drug consumption data during 2006 - 2008 were collected from the hospital information system database, and the frequency and amount were statistically analyzed. Results ： The amount of antibacterial drugs was 28.18% -29.62% of total amount. In terms of consumption amount, the first 3 were cephalosporins, quinolons and penicillins; in terms of DDDs value, the first 4 were cephalosporins, penicillins, quinolons and macrolides. The next consumption amount drugs were levofloxacin injection, ceftriaxone sodium, cefoxitin sodium, and cefuroxime sodium. The order of drugs＇ DDDs value showed fluctuation each year, and the drugs with leading DDDs value were amoxil capsules, roxithromycin capsules, ceftriaxone sodium and levofloxacin hydrochloride injection. Conclusion ： The antibacterial drug uses in our hospital is generally rational. However, the proportion of antibacterials, the antibacterials for special use, cephalosporin uses are not rational, so control remains to be tightened and the related measure should be carried out for promoting the rational uses.