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弹性纤维与盆腔器官脱垂的研究进展 被引量：2

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摘要 :盆腔器官脱垂是一种中老年妇女常见的手术率、复发率较高的疾病。近年许多临床及基础研究证实盆底支持结构中结缔组织薄弱是盆腔器官脱垂发生的病理基础。弹性纤维是盆底结缔组织的重要组成成分,赋予组织伸缩性和可逆的变形能力,维持盆底结缔组织正常结构和功能。其组成、降解稳态平衡破坏,会影响弹性纤维数量及质量,减弱盆底结缔组织的支持力,使盆底组织松弛发生器官脱垂。本文主要从弹性纤维组成过程中Fibulin-5及类赖氨酰氧化酶1(LOXL-1)等相关成分异常在女性盆腔器官脱垂发病机制中的研究做一综述。
作者 黄益娟 龚健
机构地区 南京医科大学附属无锡妇幼保健院妇科
出处 《现代医学》 2010年第4期443-447,共5页 Modern Medical Journal
关键词 盆底器官脱垂 发病机制 弹性纤维 文献综述
分类号 R711.2 [医药卫生—妇产科学]
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参考文献25

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二级参考文献18

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现代医学
2010年 第4期

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