肠黏膜生物屏障研究进展

Advances in the research of Intestinal mucosal bio-barrier

肠粘膜生物屏障是肠道粘膜屏障系统重要的一部分,本质上是由肠道内益生菌主导形成的微生态平衡系统。这一微生态系统与人体固有的肠道屏障系统相互协调、相互作用,保护人体肠道免于致病菌的侵袭。肠粘膜生物屏障本身的作用,及其与人体固有肠道屏障间的协同作用尚不十分清楚,本文就此研究进展做一综述。

Intestinal mucosal bio-barrier is an important part of the intestinal mucosal barrier system.In essence,intestinal mucosal bio-barrier is a kind of micro-ecological balance system which is dominated by the intestinal probiotics.The micro-ecosystem is able to protect intestinal mucosa against the invasion of pathogen both by itself and by synergies between it and human inherent intestinal barrier.Both biological role of intestinal barrier itself and its relationship with human inherent intestinal barrier are not very clear.This paper overviews the advancement in the mechanisms of action of Intestinal mucosal bio-barrier in recent years.