脾切除治疗68例良性血液病的效果观察

Effectiveness of splenectomy for 68 patients with benign hematopathy

目的探讨脾切除对内科治疗无效的几种良性血液病的治疗效果。方法对68例良性血液病脾切除术病人的临床资料进行回顾性分析。结果无围手术期死亡病例,术中均无大出血,根据血液学参数结果,脾切除对遗传性球形红细胞增多症、原发性血小板减少性紫癜、β型地中海贫血、α型地中篎堆⒆陨砻庖咝匀苎云堆腥非械闹瘟菩Ч?有效率分别为100%、91.3%、90.0%、72.7%及66.7%。结论脾切除术对上述良性血液病行之有效。

Objective To assess the effectiveness of splenectomy for some patients with benign hematopathy who failed to conservative treatment. Methods Sixty-eight patients with benign hema- topathy undergoing splenectomy were analyzed retrospectively. Results No patient died and had massive bleeding intraoperatively. Determination of postoperative hematological parameters indicated that splenectomy could exert significant therapeutic effects on the diseases of idiopathic hereditary spherocytosis,idiopathic thrombocytopenic purpura, β-thalassemia, α-thalassemia and autoimmune hemolytic anemia with the effective rate being 100%、91.3%、90.0%、72.7% and 66. 7 0%, respectively. Conclusion Splenectomy is effective for treatment of some benign hematopathy.