不同体质类型缺血性脑卒中患者临床特点的研究

Study on the Clinical Characteristics in Ischemic Stroke Patients With Different Constitution Types of Cerebral Arterial Thrombosis

目的:观察不同中医体质类型缺血性脑卒中患者的临床特点及近期预后。方法:采用前瞻性队列研究方法,参照王琦的体质分类标准分类体质,通过临床观察和量表测定,了解不同体质类型患者临床特点和发病3个月的预后(NIHSS,BI,MRS)。结果:①气郁质患者危险因素积分显著低于气虚质、阴虚质、痰湿质和瘀血质患者(P<0.05);气郁质患者NIHSS显著低于气虚质、阳虚质和痰湿质患者(P<0.05),而BI明显高于后者(P<0.05)。②3个月后不同体质类型患者NIHSS、MRS、BI不存在统计学差异(P>0.05)。结论:不同体质类型缺血性脑卒中患者神经功能和日常生活能力存在差异,但治疗后的近期预后无明显差异。

Objective：To investigate the neurological function defect,the life ability,and prognosis in IS（ischemic stroke） patients with different constitution types of TCM.Methods：This was a prospective and cohort study.The structured questionnaire of constitution was used to investigate the characteristics of body,the symptom in daily life,the feature of psychology,the tendency of suffering disease and the ability to adapt to environment,according to the criterion of Wang Qi＇s.The neurological function defect,the life ability and prognosis of IS was investigated.The data were analyzed to determine differences between different constitution types of TCM with spss13.0.Results：① The score of risk factors in patients with qi-yu type are significantly lower than qi deficiency,phlegm-damp,yu-xue and yin deficiency types;NIHSS and BI are significantly different among all constitution types.the patients of qi-yu constitution type have lower scores of NIHSS and higher BI when compared to patients of qi deficiency,yang-xu and phlegm-damp types（P 0.05）.②The outcomes after 3-months are not significantly different among all the constitution types of TCM in NIHSS,MRS and BI.Conclusion：Neurological function defect and the life ability are significantly different among the different constitution types of TCM.The outcomes after 3-months are not significantly different.