针刺与药物治疗慢性前列腺炎疗效比较的系统评价

Acupuncture Versus Medicine for Chronic Prostatitis:A Systematic Review

目的:评价针刺与药物比较治疗慢性前列腺炎的疗效。方法:按照Cochrane系统评价方法,全面收集针刺与药物比较治疗慢性前列腺炎的临床随机对照试验。用计算机检索PUBMED、EMbase、OVID、Cochrane图书馆、CBM、CNKI、VIP、万方数据库,手工检索天津中医药大学图书馆过刊资料库。结果:共纳入9个随机对照试验(共943例)。Meta分析结果显示:(1)总有效率:针刺与美满霉素[RR=1.26,95%CI(1.10,1.44)]、植物制剂(舍尼通、前列康)[RR=1.39,95%CI(1.23,1.58)]有差异,自拟中药比[RR=1.13,95%CI(0.99,1.29)]无差异。(2)Zn含量:针刺与美满霉素[WMD=1.76,95%CI(1.48,2.03)]有差异。(3)SOD含量:针刺与美满霉素[WMD=259.64,95%CI(230.06,289.22)]有差异。(4)IgE含量:针刺与氟哌酸[WMD=-0.01,95%CI(-0.01,0.00)]无差异。(5)不良反应:有2篇报道提及。1篇报道西药组出现2例体位性低血压,针刺组无,例发生;1篇未详细描述。结论:针刺治疗慢性前列腺炎与药物比较有一定治疗优势,但尚需要更多高质量的随机对照试验进一步验证和支持。

Objective：To assess the efficacy of acupuncture versus medicine on the treatment of chronic prostatitis.Methods：Randomized controlled trials（RCTs）involving acupuncture versus medicine on the treatment of chronic prostatitis were identified from PUBMED、EMbase、OVID、Cochrane library、CBM、CNKI、VIP、WANFANG Database.We also hand searched relevant journals from the library of Tianjin University of Traditional Chinese Medicine.Results：A total of 9 trials involving 943 patients were included.Meta-analyses showed that the total effective rate in the acupuncture group was difference when compared with Minocin [RR=1.26,95% CI（1.10,1.44）],plant preparations （Prostat and QIANLIE KANG Tablets） [RR=1.39,95% CI（1.23,1.58）],but smiliar with traditional Chinese drug[RR=1.13,95% CI（0.99,1.29）];As for the content of Zn difference was noted between acupuncture and Minocin[WMD=1.76,95% CI（1.48,2.03）];for the content of SOD,difference was observed between acupuncture and Minocin [WMD=259.64,95% CI（230.06,289.22）];for the content of IgE,acupuncture had similar effects to norfloxacin [WMD=-0.01,95% CI（-0.01,0.00）].Conclusion：Acupuncture is superior to medicine,and associated with few adverse reactions.Further large-scale trials are required to define the role of acupuncture in the treatment of chronic prostatitis.