原发性肠道恶性淋巴瘤66例临床分析

Clinical Analysis of 66 Cases of Primary Malignant Lymphoma in the Intestinal Tract

目的探讨原发性肠道恶性淋巴瘤的发病、诊断、治疗及预后。方法临床资料回顾性分析。结果本病例占同期恶性淋巴瘤的12．9％，66例患者平均年龄35．8岁，临床上常见状是腹痛、腹块、腹泻、便血，主要井发症为肠套叠、肠梗阻。按AnnArbo会议分期：Ⅰ期13例，Ⅱ期27例（ⅡA21例，ⅡE6例），Ⅲ期18例（ⅢA15例，ⅢE3例），Ⅳ期1例。本组病例均经病理确诊，病理类型上均属非霍奇金淋巴瘤（NHL），59例为B细胞淋巴瘤，5例T细胞淋巴瘤，2例组织淋巴瘤。结论肿瘤越大、病期越晚预后越差，病理类型以T细胞淋巴瘤预后最差；手术、化疗加放疗疗效最佳。

Objective To study the clinical feature, diagnosis,treatment and prognsis of primary malignant lymphoma of the intestinal tract.Methods The clinical material are retrospectively analysed.Results The disease is rareaccounting for 12.9% of all the maligmant lymphomas in the same period.The average age was 35.8. The common complaints are abdominal pain and mass, diarrhea and hemafecia ,They were complicated by intussusception or intestinal ob struction. By AnnArbo, there were 13/66 of stage Ⅰ,27/66 of stage Ⅱ, 18/66 of stage Ⅲ and 1/66 of stage Ⅳ.Patho logically all the cases were of NHL, of which 59 were B cell lymphomas,5 T cell and the others histocytic types.Conclu sopm The prognosis is aggravated by a large tumor mass, advanced stage, land T cell lymphoma in pathology. The combina[