50例健康老年人肺功能10年随访观察

A 10year followup study on lung functions of 50 healthy elderly

目的为临床和基础研究提供健康老年人肺功能各项指标随增龄改变的参考资料。方法采用日本Ｃｈｅｓｔａｃ６５型肺功能检查仪，按常规方法进行肺功能检查。结果用力肺活量（ＦＶＣ）每年下降００３２Ｌ，第１秒用力呼气量（ＦＥＶ１）每年下降００３Ｌ，ＦＥＶ１占用力肺活量比值（ＦＥＶ１％）每年下降０１５１％，呼气流量峰值（ＰＥＦＲ）每年下降０１１８Ｌ／ｓ，最大呼气中段流量（ＭＭＥＦ）每年下降００４Ｌ／ｓ，最大通气量（ＭＶＶ）每年下降０８７６Ｌ，肺活量（ＶＣ）每年下降００４Ｌ，残气容积（ＲＶ）每年升高００３３Ｌ，功能残气量（ＦＲＣ）每年升高００３３Ｌ，残气容积／肺总量（ＲＶ／ＴＬＣ）每年升高０５９６％。戒烟组的健康老年人ＶＣ、ＦＶＣ、ＦＥＶ１、ＲＶ、ＲＶ／ＴＬＣ与从不吸烟健康老年人比较差异有显著性；不同年龄组的健康老年人肺功能下降不明显。结论肺功能各项指标随增龄而改变，健康老年人各年龄组肺功能改变不明显，吸烟对健康老年人肺功能改变有一定影响。

Objective To observe the changes of lung functions with increase of age in elderly. Methods The lung functions were measured with routine examination methods by chestac65 type for lung function. Results Forced vital capacity(FVC) decreased 0032 L per year. The forced expiratory volume in first second(FEV1) decreased 003 L per year, FEV1/FVC%(FEV1%) decreased 0151%, peak expiratory flow rate(PEFR) 0118 L/s, maximal midexpiratory flow (MMEF) 004 L/s, maximal voluntary ventilation(MVV) 0876 L, vital capacity(VC) 004 L. Residual volume(RV) increased 0033 L per year, functional residual capacity(FRC) 0033 L. VC,FVC,FEV1,RV,RV/TLC of healthy elderly in the exsmoker group were significantly different from nonsmokers. The declinations of lung functions were not significant in different age group of healthy elderly. Conclusions The lung functions change with increase of age. The decrease of MVV is most marked. MMEF,VC,FVC,FEV1,FEV1%,PEFR also decrease annually. RV and FRC increase per year. Changes of VC,FVC,FEV1,RV,RV/TLC of healthy elderly in the exsmoker group compared with those of nonsmoker group are significant. Changes of lung function are not significant in different age group of healthy elderly.