阿立哌唑治疗首次躁狂发作的临床研究

The clinical study about the therapeutic effect of Aripiprazole in the first vesania

目的:研究阿立哌唑治疗首次躁狂发作的疗效。方法:47例入组患者分为两组,分别予以阿立哌唑和碳酸锂治疗,以BRMS评定疗效,以TESS评价副反应。结果:两组均于第2周末较治疗前有改善,两组间疗效无显著差异,但阿立哌唑组副反应明显少于碳酸锂组。结论:阿立哌唑治疗首发躁狂发作疗效与碳酸锂相当,安全性更高。

Objective：To investigate the therapeutic effect of Aripiprazole in the first vesania.Methods：47 patients were treated by Aripiprazole or Lithium carbonate respectively,and the therapeutic effect was evaluated by BRMS,the adverse reaction was evaluated by TESS.Results：Obvious therapeutic effect can be seen in the two groups when they were treated after two weeks,and there are no significant diference between two groups,but the Aripiprazole group had fewer side effects.Conclusion：Compared with Lithium carbonate,Aripiprazole had equal therapeutic effect but fewer side effects.