抗精神病药对多种代谢影响的研究

Investigation of the effects of antispsychotic drug on metabolism

目的:探讨长期应用抗精神病药,尤其新型抗精神病药应用是否导致肥胖、高血糖、高血脂、高血压等代谢紊乱。方法:采用自编一般情况调查表对3家民政精神卫生中心住院精神分裂症患者726例进行调查。结果:非典型抗精神病药对代谢的影响大于典型抗精神病药。结论:虽然新型抗精神病药对心血管等内脏器官影响较小,但对血糖、血脂、MBI、血压的影响不容忽视。

Objective：To discus the effects which with new antispsychotic drug on metabolism,for example which effect： fatness,hyperglycemia,hyperlipidemia,hypertension.Methods：A self-designid investigation forms were used one by one,726 in patients are from 3 civil hosptial.Results： The effect in typical antispsychotic drng is higher than antypical antipsychotic therapies.Conclusion：Although typical antispsychotic drug that less side-effects with cardiovascular effectss but can influence glucose,cholesterin,blood pressure,MBI.