肺炎支原体感染诱发儿童哮喘60例临床疗效分析

Clinical Analysis on 60 Cases Childhood Asthma Induced by Mycoplasma Pneumonia Infection

目的:探讨肺炎支原体(MP)感染诱发儿童哮喘的临床特征及联合用药的临床效果。方法:将肺炎支原体感染诱发的哮喘患儿60例随机分为观察组和对照组,对照组给予阿奇霉素和红霉素治疗,观察组给予阿奇霉素、红霉素及喘乐宁联合治疗,总结临床资料并随访观察治疗效果。结果:观察组咳嗽消失时间以及最大峰流速均优于对照组,两者比较差异具有统计学意义(P<0.05)。观察组复发率、抗体阳性率以及复发出现时间均优于对照组,两者比较差异具有统计学意义(P<0.05)。结论:肺炎支原体感染诱发的儿童哮喘临床表现多样,阿奇霉素、红霉素及喘乐宁联合治疗效果确切。

Objective： To investigate the clinical feature of childhood asthma induced by mycoplasma pneumonia infection and the effect of drug combination.Method： The 60 cases with childhood asthma induced by mycoplasma pneumonia infection were divided into the observation group and the control group.The control group received the treatment of azithromycin and erythromycin,and the observation group received the treatment of azithromycin and erythromycin combined with salbutamol.The clinical data was summarized and the effect was followed-up.Result： The extinction time of cough,maxlmum peak flow rate in the observation group were superior to those in the control group,and there were significant difference in them respectively（P〈0.05）.The relapse rate,antibody masccline rate and the time of relapse in the observation group were superior to those in the control group,and there were significant difference in them respectively（P〈0.05）.Conclusion： The clinical manifestation of asthma induced by mycoplasma pneumonia infection is multiplicity and the effect of drug combination is obvious.