摘要
为了观察逐痰通络汤对腰椎间盘突出模型大鼠的利水和消炎作用,利用腰椎间盘突出压迫神经根模型,在造模用药后4天、10天、30天进行血液流变学及神经根局部组织炎症介质(前列腺素E2、组织胺)含量测定。结果表明,逐痰通络汤能够改善全血低切粘度、红细胞聚集指数等血液流变学的状态,降低神经根局部炎症介质水平,从而证实逐痰通络汤对腰椎间盘突出动物有利水、消炎作用。
In order to observe the diuretic and anti inflammatory effect of “ZHUTAN TONGLUO TANG” (ZTT, Decoction for Removing Phlegm and Dredging Collaterals) on rat model with lumbar intervertebral disc hernia (LIDH), rat models of LIDH compressing the nerve root were used, the blood rheology and the levels of inflammatory media (prostaglandin E 2 and histamine) in the local nerve root tissues were measured 4 days, 10 days and 40 days after the modelling and the administration, respectively. The results showed that ZTT functions to improve the blood rheological indices and reduce the levels of inflammatory transmitters in the local compressed nerve root, thereby proving the diuretic and anti inflammatory effect of ZTT on LIDH animal models.
出处
《中医正骨》
1999年第6期6-7,共2页
The Journal of Traditional Chinese Orthopedics and Traumatology
基金
上海市卫生局科技发展项目
关键词
腰椎间盘突出症
中医药疗法
逐痰通络汤
lumbar intervertebral disc hernia/TCM therapy blood rheology inflammatory medium “ZHUTAN TONGLUO TANG”/therapeutic application experimental study animal rat