摘要
目的对传染性单核细胞增多症(IM)的三种实验室诊断方法进行比较,以寻求一种对IM快速诊断的实验方法。方法对162例临床诊断为IM患儿的血常规、异型淋巴细胞分类计数(AL)、血清嗜异性抗体(HA)及EB病毒抗体(EBV-CA-IgM和EBV-CA-IgG)的敏感性进行比较,分析三种实验室诊断方法正确识别IM的能力。结果 IM患儿外周血AL阳性率41.4%,HA阳性率43.8%,EBV-VCA-IgM阳性率87.7%,EBV-CA-IgG阳性率59.9%,EBV-CA-IgM诊断IM敏感性显著高于AL与HA(2χ分别为75.83,69.08,P<0.01)。结论 EBV-CA抗体检测对于早期诊断IM具有十分重要的意义,而且方法简便快速,适宜在基层医院开展。
Objective To compare three Methods of laboratory diagnosis of infectious mononucleosis（IM） to explore a method for rapid diagnosis of infectious mononucleosis.Methods We compared the Results of routine blood test,atypical lymphocyte（AL）,heterophile antibody（AH） and EB virus antibody（EBV-CA-IgM and EBV-CA-IgG） of 162 cases of IM to analyze the capacity of three Methods of laboratory diagnosis for identifying IM.Results In the children with IM,the incidence of AL in peripheral blood was 41.4%,the incidence of HA was 43.8%,the incidence of EBV-VCA-IgM was 87.7%,and the incidence of EBV-CA-IgG was 59.9%.The sensitivity of EBV-CA-IgM was significantly higher than AL（x2=75.83,P0.01）and HA（x2=69.08,P0.01） EBV-CA-IgG in diagnosis of IM.Conclusion Detection of EB virus antibody is of great importance for early diagnosis of IM.It is fast and convenient,which is suitable for the basic hospitals.
出处
《实用医院临床杂志》
2010年第5期103-104,共2页
Practical Journal of Clinical Medicine
