摘要
目的:了解B细胞发育与B细胞抗原受体(BCR)基因重排。方法:通过相关文献的阅读,综合评述B细胞发育与BCR基因重排。结果:在B细胞发育过程中伴随着BCR基因的重排,包括第一次重排和受体编辑(第二次重排),其中的一些重要事件已经被发现。结论:B细胞发育及BCR基因重排是一个密切相关的十分有序的过程,但仍有许多问题未弄清楚。
Objective:To understand the B lymphocyte development and BCR gene rearrangement.Methods:To read the related literatures then to review and comment the B lymphocyte development and BCR gene rearrangement.Results:During the B cell development,BCR gene rearrangement also occurred.The rearrangement includes primary rearrangement and receptor editing (secondary rearrangement).The some important events in this process were proclaimed.Conclusion:B lymphocyte development and BCR gene rearrangement is an ordered sequence.However,a lot of events in this procedure are unclear.
出处
《大理学院学报(综合版)》
CAS
2010年第6期28-31,共4页
Journal of Dali University
基金
国家自然科学基金资助项目(30860262)