^(89)Sr及^(89)Sr联合博宁治疗多发骨转移癌的疗效观察

Effect of ^(89)Sr and ^(89)Sr with Bonin on multiple bone metastasis

目的观察89Sr及89Sr联合博宁(帕米磷酸二钠)治疗肿瘤晚期多发骨转移癌的疗效。方法 56例恶性肿瘤多发骨转移癌随机分为89Sr治疗组(单纯组)和89Sr+博宁组(联合组)各28例。结果单纯组镇痛缓解率82.14%,联合组镇痛缓解率92.86%;骨病灶好转率单纯组75.0%,联合组85.71%,生活质量得到相应改善。结论 89Sr对肿瘤全身多发骨转移癌具有较好的缓解疼痛作用,并可延长患者生命,而联合博宁更能提高疗效和生活质量。

Objective To observe the efficacy of 89Sr and ^89Sr with Bonin for multiple bone metastasis.Methods 56 patients were randomly divided into two groups,including the simple ^89Sr treatment,Bonin and ^89Sr treatment.Results The effective rate of simple group and combination group were 82.14% and 92.86%,respectively.The effective improvement rate of the bone focus were 75.0% and 85.71%.There was homologous improvement in general conditions.Conclusion It has certain effect to treat multipie bone metastases with ^89Sr combined with Bonin.