AgNoR 图像分析在子宫颈鳞癌中的定量研究

Quantitative Study on AgNoR Imaging Analysis in the Squamous Cell Carcinoma of Cervix

采用 Ａｇ Ｎｏ Ｒ 图像分析技术测定了４１ 例宫颈良恶性病变细胞内的 Ａｇ Ｎｏ Ｒ。发现正常宫颈、宫颈不典型增生、鳞癌（ Ⅰ～Ⅲ级） 细胞核内的 Ａｇ Ｎｏ Ｒ 颗粒数、粒面积、粒面积 核面积逐级增加，颗粒直径逐级减小。结果表明， Ａｇ Ｎｏ Ｒ 定量研究对于鉴别宫颈良恶性病变、组织学分级及预后评估等有重要价值。

The AgNoR content of fourty one examples with benign and malignant cervical lesions were determined by using Automatic imaging Analysis.The result showed that in the cell mucleus of normal cervical epithelium,cervical atypical,hyperplasia,squamous carcinoma(one～three grades),average amout and area of AgNoR pellets,ratio of pellet area and cell nucleus increased following the growing of malignant extent,but pellet diameter decreased progressively.It indicate that there are significant value to differentiate benign and malignant cervical pathological changes,histological grade,prognostic evaluation etc by using AgNoR Imaging Analysis.