甲状腺功能亢进并周期性麻痹的临床分析

Clinical Analysis of Primary Hyerthyroidism Associated with Periodic Paralysis

目的探讨原发性甲状腺功能亢进并周期性麻痹的发病机制与治疗。方法回顾2006～2009年我科收治的28例原发性甲状腺功能亢进并周期性麻痹患者的临床资料并结合文献分析。结果全组25例有明显诱因，均以发作性双下肢对称性进行性麻痹为首发症状来诊，意识均清楚，四肢不同程度的无力，伴尿潴留2例，28例均合并血钾降低。治疗疗程1．5—2年，随访1年甲亢及周期性麻痹均无发作，本组全治愈。结论原发性甲状腺功能亢进常合并周期性麻痹，注意鉴别，避免误诊，积极有效地控制甲亢和补钾治疗是治疗的关键。

Objective To explore the pathogenesis and treatment of primary hyerthyroidism associated with periodic paralysis. Methods A retrospective analyzed was made of the clinical data of 28 cases of primary hyerthyroidism associated with periodic paralysis in our hospital from 2006 to 2009. Results In 28 cases, 25 cases had obvious incentive, with symmetry paralysis of double lower limbs as initial symptom, clear consciousness and different degree of Iimb weakness, and 2 cases were associated with urinary retention. All 28 eases were complicated with a decreased serum potassium level, with the treatment duration of 1.5-2 years and the follow-up of one year, and all were cured. Conclusion We should pay more attention to the identification of primary hyerthyroidism associated with periodic paralysis and avoid its misdiagnosis, and its therapy key is to control hyperthyroidism and supplement potassium.