经皮冷冻治疗644例肺癌的常见并发症分析及处理

Complications of Cryoablation in 644 Lung Cancer Patients and its Treatment

背景与目的肺癌患者大部分确诊时已属中晚期,失去了手术机会。冷冻疗法是一种可选择的安全有效的局部消融疗法。本研究旨在分析经皮冷冻治疗中晚期肺癌的常见并发症。方法 644例不能手术切除的肺癌患者在CT和/或B超下行经皮冷冻治疗,观察心血管系统和呼吸系统并发症的发生率,并采取相应的处理措施。结果肺癌经皮冷冻治疗的一般并发症程度较轻,对症处理即可恢复。严重并发症包括心脏骤停、血气胸等,重在预防。结论经皮冷冻治疗不可切除的肺肿瘤是一种简单、有效且相对安全的方法,但要注意预防并发症的发生。

Background and objective Most lung cancer patients present an advanced stage at diagnosis without suitable surgical chances.Cryotherapy has been applied to the advanced lung cancer with safety and effectiveness.The aim of this study is to analyze the most common complications that occur after percutaneous cryoablation when applied to advanced lung cancer.Methods Total 644 lung cancer patients had been treated with percutaneous cryoablation guided by ultrasound and/or CT scan.The cardivascular and respiratory complications were monitored.Results Complications were relatively minor and could be controlled with routine methods.Serious complications included cardiac arrest and hemopneumothorax,and thus preventative steps should be taken.Conclusion Percutaneous cryoablation for lung cancer is a simple,effective and relatively safe method,but attention should be paid to the possible complications during cryoablation.