曲马朵复合芬太尼在胰腺切除术术后镇痛的疗效观察

Effect of scopolamine-tramadol-fentanyl mixture for patient-controlled analgesia after hysterectomy.

目的研究曲马朵-芬太尼复合液在胰腺切除术后镇痛的效果及不良反应。方法ASAⅠ-Ⅱ级行胰腺切除术患者30例，随机分为曲马朵组和氟哌利多组，每组15例。均以0．9％氯化钠注射液配置100ml药袋，静脉给予负荷剂量5ml后连接镇痛泵进行患者自控镇痛（PCA）。结果氟哌利多组术后24h镇静评分比曲马朵组高（P〈0．05），不良反应发生率氟哌利多组明显高于曲马朵组。结论曲马朵配伍芬太尼术后镇痛安全有效，不良反应发生率明显低于氟哌利多。

Objective To study the efficacy and side effects of tramadol combined with and fentanyl for pa- tient-controlled analgesia（PCA） after pancreatectomy. Methods 30 ASA I-II patients were randomly divided into tra- madol group（ group A）and droperidol group （group B）. Results Sedation score in group B at 24 h was significantly higher than that in groiap A（ P 〈 0. 05 ）. Side-effects were significantly more in group B than those in group A. Condusion The analgesia efficacy of tramadol combined with and fentanyl was effective and safe with less side effects than Droperidol