RNA的可变剪接

Alternative RNA Splicing

在高等真核生物基因组中存在大量的割裂基因,而这些割裂基因的mRNA却是非割裂结构,在这个转化过程中去除内含子的过程就成为RNA的剪接或剪接RNA(RNA splicing)。RNA剪接特别是可变剪接是真核基因表达调控研究的重要内容之一。介绍了RNA可变剪接的特点、功能与调控、可变剪接基因以及剪接形式的识别,并对可变剪接的应用进行了举例。

There are a large number of splicing genes in higher eukaryotic genome,but these mRNA is of non-splicing structure.RNA splicing means removing introns in the transformation process.RNA splicing,especially variable RNA splicing,is an important part of regulation of eukaryotic gene expression.The paper describes the characteristics,function and regulation of RNA splicing,alternative splicing genes,and identification of splicing forms.Some samples were taken to introduce the application of alternative RNA splicing.