肿瘤-睾丸抗原的功能与肿瘤免疫治疗

Functions of tumor- testis antigen and its application for tumor immunotherapy

肿瘤-睾丸抗原（CTA）是一类肿瘤相关性抗原，在多种肿瘤组织中表达，仅在少数正常组织表达。CTA功能众多，至今仍未完全明了，该抗原具有致免疫原性，在体内可产生细胞和体液免疫应答，为肿瘤免疫治疗提供了新的途径。

Cancer-testis antigen （CTA） is a kind of tumor-associated antigen, which expresses in various types of human tumor tissues but only express in a few of normal tissues. The CTA has numerous functions that not yet are fully understood. The CTA possesses immunogenicity that may induce cellular and humoral responses in vivo, which can provide a new approach for cancer immunotherapy.