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cyclinE与p27在乳腺癌中的研究进展

Prospect for research on cyclin E and p27 in breast cancer
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摘要 细胞周期调控紊乱是乳腺癌重要发病机制之一，而cyclin E和p27是细胞周期最重要的调节因子。研究表明，cyclin E和p27具有评估乳腺癌预后的能力，且与其他生物学指标相比，与乳腺癌预后相关性更大。 Deregulation of cell cycle is one of important mechanisms leading to breast cancer. It has been revealed that cyclin E and p27 are the most important regulatory factor for cell cycle control and a better marker for evaluating prognosis of breast cancer compared to other biological markers.
作者 张月君(综述) 高学健(综述) 王本忠(审校) 张敬杰(审校)
机构地区 安徽滁州市第一人民医院外
出处 《国际肿瘤学杂志》 CAS 2010年第6期445-448,共4页 Journal of International Oncology
关键词 细胞周期 细胞周期蛋白E 周期素依赖蛋白激素抑制剂p27 乳腺肿瘤 Cell cycle Cyclin E Cyclin-dependent kinase inhibitor p27 Breast neoplasms
分类号 R735.2 [医药卫生—肿瘤]
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参考文献30

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国际肿瘤学杂志
2010年 第6期

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