胸腺瘤合并重症肌无力诊疗策略

The diagnosis and treatment strategy of thymomas associated with myasthenia gravis

胸腺瘤合并重症肌无力（MG）发病机制尚未完全明确，其诊断通过临床表现、影像学及实验室检查并无困难，但治疗方法存在争议且尚无明确治疗原则。多数学者认为，胸腺瘤合并MG患者应首选手术，对于不宜手术者可以考虑放疗及化疗，同时配合抗胆碱酯酶药及类固醇药物治疗。

The mechanism of development of thymomas associated with myasthenia gravis（MG） is not completely clear. It is not hard to make diagnosis of thymomas associated with MG via clinical manifestation, radiological investigation and laboratory examination, however, the treatment of thymomas associated with MG remains controversial and there is no straightforward guidelines in the literatures. Most scholars think surgery is the first choice to treat thymomas associated with MG, but for those who are not suitable for surgery, radiothera- py and chemotherapy would be considered to be their choice combined with anti-cholinesterase and steroids drugs therapy.