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整合素与肿瘤血管新生

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摘要 整合素(integrin)是广泛分布于细胞表面的跨膜糖蛋白,是一个细胞表面受体家族,属黏附分子中的一大家族,能与其他细胞黏附因子相互作用,也是细胞外基质(ECM)的主要受体,介导细胞黏附[1].作为介导信号传递的膜分子通过独特的途径转导信号,借此大量的细胞表型由整合素调节,包括细胞的生长、分化、游走和移行、侵入、凋亡等.
作者 张帆 李敏
出处 《中国骨肿瘤骨病》 2010年第4期364-367,共4页 Chinse Journal Of Bone Tumor And Bone Disease
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