手术分娩对产妇和新生儿B细胞的影响

Influence of Surgery Childbirth Way on Parturient Woman and Newborn Blood B Cells Quantity

目的:探讨手术分娩对产妇和新生儿血中B细胞数值的影响。方法:选择足月分娩产妇60例:其中自然分娩(NL)组、择期剖宫产(CS)组、经试产而急诊剖宫产(CS-E)组各20例。分娩时分别采集产妇外周血和新生儿脐血,采用流式细胞仪检测血中B细胞CD19+的百分数。结果:CS-E组产妇血中B细胞数(10.53±3.26%)明显高于NL组(7.81±2.90%)和CS组(6.89±4.72%)(P<0.01);新生儿脐血中B细胞数CS组(8.63±5.78%)低于NL组(12.95±5.37%)和CS-E组(12.48±5.42%)(P<0.05)。结论:CS-E产妇血中B细胞值的明显增高,可能与产妇分娩发动及胎儿状况有关;CS组新生儿脐血中B细胞数减少,可能会增加新生儿对某些病原体的易感性。

Objective：To evaluate the influence of surgery childbirth way on parturient woman and newborn B cells quantity.Methods：A total of 60 term delivery parturient women were selected and divided into 3 groups：the natural labor group（NL group）,the c-section with selected data group（CS group）,the c-section with emergency medical treatment group（CS-E group）,each group was 20 cases.When the childbirth separately the parturient woman peripheral blood and the newborn cord blood were adopted.B cells CD19＋ percentage was examed by the flow cytometry.Results：The number of the parturient woman peripheral blood B cells in the CS-E group was significantly larger than that in the NL group and the CS group（P〈0.01）.The number of the newborn cord blood B cells in the CS group was significantly larger than that in the NL group and the CS-E group（P〈0.05）.Conclusion：The peripheral blood B cells with the increase in parturient woman of CS-E may be associated with the childbirth start up and the state of the fetus.CS causes the newborn cord blood B cells number reduce,possibly will increase the susceptibility to certain pathogen.