右半肝活体肝移植验证标准肝体积公式

Evaluation of standard liver volume formulas by right liver living donor liver transplantation

目的 分析216例活体肝移植患者的临床资料,探讨适合中国成人活体肝移植肝体积评估标准.方法 华西医院移植中心2001年7月至今共实施216例活体肝移植,选取符合标准的成人间活体右半肝（不含肝中静脉）179例肝移植供体,将供体的术中实测右半肝体积与CT测量右半肝体积以及各公式计算的标准右半肝体积进行比较,评估哪种公式更适合中国成人.结果 CT测量右半肝体积大于实际右半肝体积（P＜0.01）.德国Heinemann、美国Yoshizumi、日本Urata、美国Vauthey、韩国Lee公式计算的右半肝体积结果显著大于实际肝脏体积（P＜0.01）.香港Sheung Tat 公式计算的右半肝体积结果小于实际肝脏体积,差异有统计学意义（P＜0.05）.华西Lünan-yan公式计算的右半肝体积结果与实际肝脏体积比较差异无统计学意义（P＞0.05）.结论 华西Lünan-yan 标准肝体积公式适合中国成人活体肝移植标准肝体积评估.

Objective To evaluate the suitability of reported standard liver volume formulae for Chinese adults based on the practice of 216 cases of living donor liver transplantation in our transplantation center. Methods The graft volume was preoperatively estimated in 179 adult-to-adult right liver living donors by two methods： first, the radiological right liver volume by computed tomography （CT） and second,calculated graft volume obtained by reported standard liver volume formula and the percentage of the right liver volume （ given by CT）. Both results were compared to the actual graft volume measured during surgery.Results The mean percentage of right liver volume was 55.4% （SD 5.41%）. The results of Urata、Heinemann、Vauthey、 Lee、 Yoshizumi formula were significantly larger than the actual right liver volume （P 〈0. 01 ）. The result of Sheung-tat Fan was less than the actual right liver volume, there was statistical ESLV =334. 024 ＋ 11. 508 × BW, is most suitable to estimate adult Chinese donor＇s right liver volume.